Moringa oleifera Leaf Ethanol Extract Inhibits Toxoplasma gondii Tachyzoites Replication
نویسندگان
چکیده
The various infection routes of Toxoplasma gondii that are close to daily life strongly support the incidence toxoplasmosis. emergence drug-resistant strains raises future concerns. Moringa leaf ethanol extract has been shown have several anti-pathogen activities, which could an anti-Toxoplasma effect. This research was conducted analyze effect moringa against tachyzoites replication in and correlation between doses with number tachyzoites. Mice were divided into five groups. negative control group (Group I) received CMC-Na solution. positive II) spiramycin 100 mg/kg BW. treatment groups 250 BW (group III), 500 IV), 1000 V), respectively. injected 1 x 105 tachyzoites/0.1 mL/mice intraperitoneally on first day. given orally once for three days. intraperitoneal fluid calculated fifth results there significantly lower differences (P < 0.05) IV = 0.021) V 0.022) compared I. There also a significant 0.000; r -0.781). oleifera by inhibiting tachyzoite at
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ژورنال
عنوان ژورنال: Indonesian Journal of Tropical and Infectious Disease
سال: 2023
ISSN: ['2356-0991', '2085-1103']
DOI: https://doi.org/10.20473/ijtid.v11i1.42672